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Indels in non-coding DNA also contribute to cancer
Indels in non-coding DNA also contribute to cancerCancer is a large group of diseases characterized by uncontrolled growth of abnormal cells in the body. These abnormal cells harbor the potential to invade other parts of the body. The World Health Organization says that...
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Study uncovers a connection between hyperglycaemia and Alzheimer's disease
Study uncovers a connection between hyperglycaemia and Alzheimer's diseaseAccording to a study published in the journal Scientific Reports, researchers at the University of Bath have made a breakthrough in understanding the pathogenesis of Alzheimer's disease, the most common type of dementia....
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Some patients with uterine leiomyosarcoma may respond to PI3K/mTOR inhibitors
Some patients with uterine leiomyosarcoma may respond to PI3K/mTOR inhibitorsUterine sarcoma is a rare cancer that occurs when malignant cells form in the muscle and supporting tissues of the uterus. Uterine sarcomas are heterogeneous tumors and usually have an aggressive clinical behavior. Based...
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Inhibiting PAK1 increases survival of mice with pancreatic cancer
Inhibiting PAK1 increases survival of mice with pancreatic cancerAustralian researchers identify PAK1 as a regulator of the activation, proliferation and apoptosis of pancreatic stellate cells. The study, led by researchers from University of Melbourne and University of New South Wale...
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BTK regulates inflammation activation
BTK regulates inflammation activationInflammation is the body's attempt to remove harmful stimuli, including damaged cells, pathogens and irritants, and to initiate healing of tissue. It is a protective response involving host cells, blood vessels and prote...
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Newly identified mutations in bacteria confer resistance to multiple antibiotics
Newly identified mutations in bacteria confer resistance to multiple antibioticsIn an article published in eLife, a team led by Deborah Hung at The Broad Institute of MIT and Harvard report that they have identified new bacterial mutations that help resist antibiotic treatment. Antibiotics are am...
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Deeper understanding of how macrophages fight against microbes
Deeper understanding of how macrophages fight against microbesA latest study provides an insight into how the innate immune system senses foreign DNA and combat infections. The innate immune system, or called in-born immune system, is a non-specific immune defense against infect...
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New clues to mechanism of thyroid cancer
New clues to mechanism of thyroid cancerThyroid cancer occurs when abnormal cells grow in the thyroid gland, an organ that makes hormones to regulate heart rate, blood pressure, body temperature and weight. The cancer is relatively uncommon compared to other c...
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Approach to monitor the effect of annual flu vaccination
Approach to monitor the effect of annual flu vaccinationIn an article published in Science Immunology, E. John Wherry and co-workers report that they have found an approach to detect a type of circulating helper T cells in the blood after an annual flu vaccine. The approach w...
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Warburg effect contributes to cancer development
Warburg effect contributes to cancer developmentAbout a century ago, a German biochemist named Otto Warburg noticed that cancer cells fundamentally change their metabolism. For example, cancer cells exhibit increased rate of glycolysis even in the presence oxygen. The...
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Study solves a mystery about AML
Study solves a mystery about AMLWriting in the Journal of Experimental Medicine, a team of researchers from Leibniz Institute for Experimental Virology, Engelhardt Institute for Molecular Biology, Johann Wolfgang Goethe-University and Linköping Univer...
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Michigan researchers uncover a new mechanism of hidden hearing loss
Michigan researchers uncover a new mechanism of hidden hearing lossDescribed in Nature Communications, a study reveals a second cause of hidden hearing loss, an auditory neuropathy that contribute to speech discrimination and intelligibility deficits in individuals considered to have no...
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New discovery brings hope for Alzheimer's patients
New discovery brings hope for Alzheimer's patientsAlzheimer's disease is a form of dementia that impairs memory, thinking, and behavior. The disease predominantly affects people over the age of 60. Symptoms develop slowly and get worse over time, eventually interfering ...
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Scientists identify a mutation that influences infectivity of flaviviruses
Scientists identify a mutation that influences infectivity of flavivirusesFlavivirus is a genus of viruses in the family Flaviviridae, including about 75 species. It includes the West Nile virus, dengue fever virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and some other v...
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Nodding syndrome may be caused by immune responses to parasite
Nodding syndrome may be caused by immune responses to parasiteDescribed in Science Translational Medicine, a study provides clues to the pathogenesis of Nodding syndrome, a unique seizure disorder affecting children in certain countries in East Africa. The study was conducted by in...
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Study provides a powerful weapon against schistosomiasis
Study provides a powerful weapon against schistosomiasisSchistosomiasis is a detrimental disease caused by parasitic flatworms called schistosomes. It is one of the most common parasitic diseases in the world. According to the World Health Organization estimates, schistosomia...
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Researchers find a genetic signature of type 2 diabetes
Researchers find a genetic signature of type 2 diabetesType 2 diabetes (T2D), the most common form of diabetes, is a long-term disorder in which the body does not use insulin properly. This is called insulin resistance. Insulin is a hormone that lets the cells turn glucose f...
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Research reveals the role of SMN protein in spinal muscular atrophy
Research reveals the role of SMN protein in spinal muscular atrophySpinal muscular atrophy, which is the leading genetic cause of early childhood lethality, is a disease that affects motor neurons in the spinal cord. The disease is caused by alterations in the SMN1 gene, which codes for...
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