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Promising way to reverse aging
Promising way to reverse agingFindings of a new study published in Science could lead to effective anti-ageing drugs. The study, led by researchers from Harvard Medical School, University of Rochester, Mayo Clinic, University of Bayreuth, and The ...
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Research links OTUD6B gene to an intellectual disability syndrome
Research links OTUD6B gene to an intellectual disability syndromeFor the first time, scientists have found that a gene called OTUD6B is involved in human disease. The study, led by researchers at Baylor College of Medicine, has shown that mutations in OTUD6B can cause physical and int...
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Why exercise improves bone health?
Why exercise improves bone health?Specific exercises such as resistance training and jump training can improve bone health, according to a study published in the journal Bone. The study is carried out by researchers including Pamela Hinton, Peggy Nigh, a...
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Heroin addiction is associated with epigenetic impairments
Heroin addiction is associated with epigenetic impairmentsOpiate abuse and overdose have become a major public health concern. To understand the molecular basis of opiate addiction, scientists have carried out many experiments in animal and in vitro models. But little is known ...
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Inhibition of en enzyme reduces depression symptoms in mice
Inhibition of en enzyme reduces depression symptoms in miceAs a common mood disorder, depression is estimated to affect 19 million people in the USA. People with depression experience overwhelming feelings of sadness, unpleasure, guilt and hopelessness, which interfere with dail...
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Coagulation factor XII appears to play a role in Alzheimer's disease
Coagulation factor XII appears to play a role in Alzheimer's diseaseA study, led by The Rockefeller University researchers in collaboration with researchers from IONIS Pharmaceuticals Inc, has revealed that the coagulation factor XII may play a role in the development of Alzheimer's dise...
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Podoplanin protein is involved in the formation of thrombosis in cancer
Podoplanin protein is involved in the formation of thrombosis in cancerIn a paper published in the journal Blood, a research team consisting of scientists from the Medical University of Vienna and the Medical University of Graz reports that a protein called podoplanin is involved in the for...
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Hi1a protein might be a potential treatment for stroke
Hi1a protein might be a potential treatment for strokeA team of researchers headed by Professor Glenn King from The University of Queensland has identified a small protein that shows promise in reducing brain damage after a stroke.  The protein, called Hi1a, is foun...
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New therapeutic targets for mucosal melanoma identified
New therapeutic targets for mucosal melanoma identifiedMelanoma is a rare but aggressive form of skin cancer: it accounts for only 2% of all skin cancers but causes most deaths from skin cancer. Most cases of melanoma result from too much exposure to ultraviolet radiation wh...
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New clues to the mechanism of inflammatory bowel disease
New clues to the mechanism of inflammatory bowel diseaseInflammatory bowel disease (IBD) describes a group of conditions that involve chronic immune response and inflammation of the gastrointestinal tract. Ulcerative colitis and Crohn disease are the two major types of IBD. I...
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Research sheds light on how a human antibody neutralizes the Zika virus
Research sheds light on how a human antibody neutralizes the Zika virusThe Zika virus (ZIKV) has been linked to birth defects such as microcephaly and the severe autoimmune disease Guillian-Barré syndrome. One potential strategy to combat the dangerous virus is the use of neutralizing anti...
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New explanation for why sulforaphane has anti-tumor effect
New explanation for why sulforaphane has anti-tumor effectIn a paper published in the Journal of Nutritional Biochemistry, a team of researchers from Oregon State University and the Texas A&M Health Science Center has demonstrated that a natural compound found in certain ve...
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Myb regulates the function of regulatory T cells
Myb regulates the function of regulatory T cellsDescribed in the journal Immunity, a study of the University of Melbourne reveals that the transcription factor Myb modulates the function of a subtype of immune cells, called regulatory T (Treg) cells. Treg cells mai...
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Anti-CD47 antibody shows promise against childhood brain tumors
Anti-CD47 antibody shows promise against childhood brain tumorsA study led by researchers from the USA, Canada, Germany, and Switzerland now has shown that a humanized antibody that blocks the CD47 protein on tumor cells shows promise against a variety of pediatric brain tumors. The...
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Research adds to evidence that GABA is implicated in schizophrenia
Research adds to evidence that GABA is implicated in schizophreniaAccording to a paper published online in "Molecular Psychiatry," a key neurotransmitter known as gamma-Aminobutyric acid (GABA) is reduced in individuals with schizophrenia and is associated with symptom severity. The st...
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GRIN2A mutations contribute to epilepsy
GRIN2A mutations contribute to epilepsyResearchers from the King's College London and the Eli Lilly Research Centre in the UK have demonstrated how genetic mutations can lead to epilepsy-aphasia spectrum, a group of genetic epilepsy syndromes characterized by...
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Early antibody treatment provides long-lasting protection against HIV-like virus
Early antibody treatment provides long-lasting protection against HIV-like virusThere have been a series of HIV medications, such as nucleoside/nucleotide reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, fusion inhibitors, and integrase inhibito...
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A specific enzyme promotes metastasis of prostate cancer to bones
A specific enzyme promotes metastasis of prostate cancer to bonesDescribed in "Cancer Cell," a study shows that an enzyme called monoamine oxidase A (MAOA) promotes the metastasis of prostate cancer to bones. The study, led by researchers from Cedars-Sinai Medical Center, the Secondar...
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