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KCNQ1 is associated with good survival in colorectal cancer
KCNQ1 is associated with good survival in colorectal cancerColorectal cancer, or called colon cancer for short, is a type of cancer that occurs in the colon or rectum. Colorectal cancer is the third most frequent malignancy worldwide. It is responsible for approximately 774,000 ...
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Malaria protein is a useful tool in the fight against drug-resistant bladder cancer
Malaria protein is a useful tool in the fight against drug-resistant bladder cancerA protein found in the malaria parasite shows significant therapeutic effect on bladder cancer, according to a study published in European Urology. The study is conducted by an international team consisting of researcher...
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Potent dual inhibitors of TNF and RANKL identified
Potent dual inhibitors of TNF and RANKL identifiedUsing a computer-based drug screening platform, researchers have identified two compounds capable of blocking proteins involved in chronic inflammatory diseases. The study is published 20 April 2017 in PLoS Computational...
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A frog protein protects mice against flu infection
A frog protein protects mice against flu infectionEmory University researchers have found that a frog slime protein can kill flu virus. The study, published in Immunity, demonstrates that a peptide from the skin of the South Indian frog, named "urumin", is virucidal for...
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A protein in umbilical cord blood appears to improve mental ability
A protein in umbilical cord blood appears to improve mental abilityA protein found in human umbilical cord blood can make old mice smarter, a finding that may lead to new therapies for aging-related declines in mental ability, according to a study published in the scientific journal Nat...
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Study provides new clues to IBD therapy
Study provides new clues to IBD therapyA recent study published 22 March 2017 in the journal Mucosal Immunity has revealed that a specific cytokine controls whether immune cells promote or inhibit inflammatory bowel disease (IBD). The study is led by Tim Denn...
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Novel LOX inhibitor shows promise in treating cancer
Novel LOX inhibitor shows promise in treating cancerResearchers from the University of Manchester and The Institute of Cancer Research have identified a new pathway involved in the progression of breast cancer, and they have also designed a compound that inhibits this pat...
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Scientists find a way to treat motor neuron diseases
Scientists find a way to treat motor neuron diseasesResearchers from the Harvard University and Columbia University have shown that two different neurodegenerative diseases, spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS), may be treated with a commo...
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Approach to removing pathogenic antibodies in anti-MAG neuropathy
Approach to removing pathogenic antibodies in anti-MAG neuropathyAccording to a study published in the Proceeding of the National Academy of Science, synthetic carbohydrates may be used to treat anti-MAG neuropathy, an autoimmune disease of the peripheral nervous system. Anti-MAG n...
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Measuring TSPYL5 levels may help treat prostate cancer
Measuring TSPYL5 levels may help treat prostate cancer Prostate cancer is the most frequently diagnosed malignancy in adult men in developed countries. For example, in the US, one out of five men will be diagnosed with prostate cancer. Even though mortality has fallen signif...
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Combining an experimental vaccine with an existing drug increases survival of patients with glioblastoma
Combining an experimental vaccine with an existing drug increases survival of patients with glioblastomaGlioblastoma is the most common malignant brain tumor in adults. The disease is almost uniformly fatal, and the median survival is less than 15 months. Despite great breakthroughs in basic cancer research, the therapies ...
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Excessive Id1 protein may increase the risk of obesity
Excessive Id1 protein may increase the risk of obesityThe protein inhibitor of differentiation 1 (Id1) is a member of the basic HLH family of transcription factors. This protein is known to promote proliferation and inhibit differentiation. Upregulation of Id1 expression ha...
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Inhibition of ataxin-2 prolongs survival of mice with ALS
Inhibition of ataxin-2 prolongs survival of mice with ALSAccording to a study published online 12 April 2017 in the journal Nature, reduction of a certain protein prolongs survival time of mice with Amyotrophic lateral sclerosis (ALS). The study, carried out by scientists f...
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Cell replacement therapy treats Parkinson's disease in mice
Cell replacement therapy treats Parkinson's disease in miceAn international research team has found a treatment approach for Parkinson's disease, a progressive neurodegenerative disease characterized by the loss of dopamine-producing neurons in the brain. The study, described...
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Gene that increases chemotherapy effectiveness identified
Gene that increases chemotherapy effectiveness identifiedA gene called PID1 may increase the therapeutic effect of chemotherapy drugs on brain tumors, according to a study published online 11 April 2017 in the journal Scientific Reports. There are several treatment options ...
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PLK4 inhibition could be a way to treat rhabdoid tumors
PLK4 inhibition could be a way to treat rhabdoid tumorsA team of researchers from Ann and Robert H. Lurie Children's Hospital of Chicago, Stanley Manne Children's Research Institute, Northwestern University, Thermo Fisher Scientific, and Juntendo University has identified a ...
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Research opens a new avenue for treatment of leukemia
Research opens a new avenue for treatment of leukemiaIn a paper in the journal Nature Immunology, researchers describe how a protein, called STAT5, can drive the development of leukemia, a cancer of the blood cells that usually starts in the bone marrow. The study, carr...
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New method shows promise against HIV
New method shows promise against HIVResearchers in the US and China have developed a method that renders cells resistant to virus infection, according to a study published in the Proceedings of the National Academy of Sciences. The study, carried out by...
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